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CAPRYLOYL SALICYLIC ACID

Last update on May 21, 2026

Capryloyl Salicylic Acid, also known as LHA (Lipohydroxy Acid), is a lipophilic derivative of salicylic acid. It is a gentle yet effective exfoliating agent with strong keratolytic, anti-inflammatory, and antimicrobial properties. Thanks to its fatty acid chain, it penetrates the skin more gradually than regular salicylic acid, resulting in lower irritation while still delivering excellent exfoliation, smoothing, and brightening benefits. It is widely used in anti-aging serums, toners, acne treatments, and peels.

CAS Number: 70424-62-3Chem/IUPAC Name: Capryloyl Salicylic AcidEINECS/ELINCS No: COSING REF No: 32421

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What is CAPRYLOYL SALICYLIC ACID used for?

  • Exfoliating / Keratolytic: Promotes gentle skin renewal and unclogs pores. Frequently used in anti-acne and resurfacing products.
  • Skin conditioning & brightening: Improves skin texture, tone, and radiance. Ideal for anti-aging serums and treatments targeting dullness and uneven skin.
  • Anti-inflammatory & antimicrobial: Helps calm irritated skin and reduces acne-causing bacteria. Common in sensitive skin and blemish-control formulations.

Origin

Capryloyl Salicylic Acid is produced synthetically by the esterification of salicylic acid with caprylic acid (octanoic acid). The resulting molecule is lipophilic, allowing better affinity with the skin’s lipid barrier compared to water-soluble salicylic acid.

What does CAPRYLOYL SALICYLIC ACID do in a formulation?

SKIN CONDITIONING|
ANTIMICROBIAL|
SMOOTHING

Safety Profile

Capryloyl Salicylic Acid is considered safe for cosmetic use with a low to moderate hazard rating. It is generally better tolerated than pure salicylic acid, especially on sensitive skin. It may increase sun sensitivity, so daily sunscreen use is recommended. Approved by the EU COSING database for skin conditioning and exfoliating functions in leave-on products (with concentration limits in some regions).

CAPRYLOYL SALICYLIC ACID alternatives

CAPRYLOYL SALICYLIC ACID technical profile

PropertyValues
Boiling PointDecomposes
Melting Point110°C – 115°C
pH3.0 - 4.0 (in formulation)
SolubilitySoluble in oils and glycols; limited in water
ViscosityLow

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