LactoSporin®

Bacillus Ferment Filtrate. LactoSporin® by Sabinsa is a probiotic metabolite for formulating anti-acne face wash, hair care and feminine wash products. It is a non-living microbial cell product (postbiotic) purified from the culture supernatant of the probiotic strain B. coagulans MTCC 5856. It exhibits antimicrobial, anti-inflammatory and anti-collagenase properties. It also has excellent antioxidant activity with 50% inhibition of free-radical scavenging at 0.43% v/v. It shows a dose dependent reduction in reactive oxygen species (ROS) induced by UV exposure in fibroblasts, thereby protecting the skin against oxidative stress and aging. It reduces the formation of advanced glycation end-products (AGEs), ultimately improving skin tone. It also shows protective efficacy against environmental pollutants. It prevents microbial biofilm formation. It stimulates the anagen phase by increasing the proliferation of follicle dermal papilla cells and by inhibiting 5a-reductase activity. LactoSporin® is highly active against significant skin pathogens like S. aureus, S. epidermidis, Propionibacterium acne and P. aeruginosa. It is stable in acidic pH and shows thermal stability at 90°C for 30 minutes. It is non-mutagenic and is not a dermal or ocular irritant. It has a shelf life of 1 year.