AnnonaSense CLR™

Annona Cherimola Fruit Extract. AnnonaSense CLR™ by CLR Berlin is a natural and upcycled ingredient. It acts as an anti-inflammatory and rebalancing agent. It provides the skin with means to establish a sustainable homeostatic balance, improving skin health and well-being. It is obtained from Annona cherimola, common name Cherimoya, an edible fruit originating from South America; processed and dried before extracting.

• It supports the endocannabinoid system (ECS) by activating the CB2 receptor, reduces inflammatory process induced by TRPV1, down-regulates stress induced by histamine & TNFa/substance P, and reduces the expression of IL-31RA.
• It offers soothing, calming and anti-stress properties.
• It reduces sensitivity & itchiness and improves skin appearance.
• It improves well-being & sleep and reduces psychological stress. Moreover, it reduces the production of stress hormones in the body (cortisol).
• It is suitable for dry, sensitive and pruritic skin.
• It is recommended for formulating scalp care products, aqueous & emulsified skin-, face- & body care products.
• It is also used in gel type formulations and serums.
• AnnonaSense CLR™ is COSMOS approved, NATRUE and Halal certified.
• It has a shelf life of 18 months.