Papain is a powerful proteolytic enzyme naturally derived from the unripe fruit and latex of the papaya plant (Carica papaya). It is valued in cosmetics for its ability to gently break down proteins, making it an effective exfoliating and skin-renewing ingredient. Papain helps remove dead skin cells, smooth rough texture, and promote a brighter, more even complexion. It is commonly used in exfoliating masks, peels, cleansers, and anti-aging products, especially in natural and enzymatic skincare lines.
Products with PAPAIN
With samples available
Protesse G66
by Uniproma Chemical
- Sustainable option
- Original documents
EcoClear™ AcneShield
by Ecocos Biotechnologies
- Sustainable option
What is PAPAIN used for?
- Exfoliating: Breaks down keratin and dead skin cells for gentle resurfacing. Frequently used in enzymatic peels, masks, and scrubs for smoother skin texture.
- Skin conditioning: Improves skin clarity and softness by promoting natural cell turnover. Ideal for dull, rough, or uneven skin formulations.
- Soothing & anti-inflammatory: Helps reduce buildup and calm minor skin irritation. Common in clarifying treatments and products for congested or acne-prone skin.
Origin
Papain is extracted from the latex of unripe papaya fruit (Carica papaya). The latex is collected, dried, and purified to isolate the enzyme. It is a natural, plant-derived proteolytic enzyme widely used in both traditional and modern cosmetic formulations. Commercial grades are often standardized for activity and stability.
What does PAPAIN do in a formulation?
SMOOTHING|
SOOTHING|
SKIN CONDITIONINGSafety Profile
Papain is considered safe for cosmetic use at appropriate concentrations, with a low hazard rating from EWG (1-2). It is generally well-tolerated but can cause irritation or allergic reactions in sensitive individuals, especially at high concentrations. As an active enzyme, it should be used carefully in leave-on products. Not recommended for very sensitive or broken skin.
PAPAIN alternatives
PAPAIN technical profile
| Property | Values |
| Boiling Point | Decomposes |
| pH | Optimal activity at 5.0 - 7.0 |
| Solubility | Soluble in water and glycerin |
| Viscosity | Low |
Formulations with PAPAIN
No data available
By Application
No data available