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PALMITOYL TRIPEPTIDE-1

Last update on Sep 3, 2024

Palmitoyl Tripeptide-1 is widely used in cosmetics for its ability to stimulate collagen production, promote skin healing, and improve the overall appearance of the skin. This synthetic peptide contains three amino acids - glycine, histidine, and lysine - and a fatty acid that are good for the skin and increase the stability of a formulation. When added to skin care products, this ingredient aids in smoother and firmer skin over time while also healing and soothing damaged skin. In its raw form, Palmitoyl Tripeptide-1 appears as a white to off-white powder that is generally odorless. It is water soluble making it suitable for formulations like serums, creams, and gels. The chemical formula of Palmitoyl Tripeptide-1 is C₃₀H₅₄N₆O₅.

CAS Number: 147732-56-7Chem/IUPAC Name: N-palmitoyl-glycyl-L-histidyl-L-lysineEINECS/ELINCS No: 680-607-0COSING REF No: 56919

Products with PALMITOYL TRIPEPTIDE-1

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ActiTide® 3000

by Uniproma Chemical

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Matrixyl® 3000

by Croda

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MAXI-LIP™

by Brenntag Beauty & Personal Care

INCI: ETHYLHEXYL PALMITATE | PALMITOYL TRIPEPTIDE-1 | SORBITAN ISOSTEARATE | TRIBEHENIN

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What is PALMITOYL TRIPEPTIDE-1 used for?

Palmitoyl Tripeptide-1 has potent anti-aging and skin-repairing properties. By mimicking a fragment of collagen, it stimulates collagen production, helping to reduce the appearance of fine lines, wrinkles, and sagging skin. This peptide also promotes skin firmness and elasticity, making it a key ingredient in anti-aging serums, creams, and eye treatments. Additionally, Palmitoyl Tripeptide-1 supports skin healing and regeneration, improving overall skin texture and resilience. Often combined with other peptides, such as in the Matrixyl 3000 complex, Palmitoyl Tripeptide-1 enhances the effectiveness of anti-aging formulations for a smoother, more youthful complexion.

Origin

Palmitoyl Tripeptide-1 is synthesized through solid-phase peptide synthesis (SPPS), where amino acids are sequentially added to form the tripeptide. After the peptide chain is assembled, it is chemically linked to palmitic acid, a fatty acid. The final compound is then purified to remove any impurities.

What does PALMITOYL TRIPEPTIDE-1 do in a formulation?

HUMECTANT|

SKIN CONDITIONING|

SMOOTHING

Safety Profile

Palmitoyl Tripeptide-1 is considered non-toxic and safe for use in cosmetics. Extensive studies have shown that it does not cause skin irritation, sensitization, or other adverse effects when used in recommended concentrations (typically 2% to 5%). It is well-tolerated by most skin types, including sensitive skin. It is also non-comedogenic. However, a patch test should be performed to check for individual allergies.