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PALMITOYL TETRAPEPTIDE-7

Last update on Sep 3, 2024
Palmitoyl Tetrapeptide-7, a synthetic peptide, is a key ingredient in anti-aging formulations. It has collagen-boosting properties that target wrinkles and fine lines. It also helps restore the skin’s firmness and elasticity by supporting the skin’s structural components, leading to a firmer and more youthful appearance. Further, this peptide is known for its anti-inflammatory and hydrating benefits. In its raw form, Palmitoyl Tetrapeptide-7 appears as a white to off-white powder and does not affect the texture or appearance of a formulation. Since it is odorless, it is often used in fragrance-free products targeting sensitive skin. This ingredient is commonly found in anti-aging creams and serums, eye creams, and moisturizers.
CAS Number: 221227-05-0Chem/IUPAC Name: N-palmitoyl-glycyl-L-glutaminyl-L-prolyl-L-arginineEINECS/ELINCS No: COSING REF No: 56918

Products with PALMITOYL TETRAPEPTIDE-7

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Matrixyl® 3000

by Croda

INCI: BUTYLENE GLYCOL | CARBOMER | GLYCERIN | PALMITOYL TETRAPEPTIDE-7 | PALMITOYL TRIPEPTIDE-1 | POLYSORBATE 20 | AQUA
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What is PALMITOYL TETRAPEPTIDE-7 used for?

Palmitoyl Tetrapeptide-7 is widely used in cosmetics for its anti-aging and anti-inflammatory properties. It is commonly found in serums, creams, and eye treatments, helping to reduce fine lines, wrinkles, and sagging skin by promoting collagen production and improving skin elasticity. It also reduces inflammation by inhibiting the release of pro-inflammatory cytokines, making it ideal for sensitive or irritated skin. Additionally, it helps to improve overall skin texture, firmness, and hydration. Palmitoyl Tetrapeptide-7 is frequently included in formulations designed for mature or damaged skin, offering long-term benefits with consistent use.

Origin

Palmitoyl Tetrapeptide-7 is synthesized by combining a tetrapeptide, composed of four amino acids (glycine, glutamine, proline, and arginine), with palmitic acid, a fatty acid. This process involves solid-phase peptide synthesis (SPPS), where amino acids are sequentially added to form the peptide chain. After the peptide is assembled, it is attached to the palmitic acid to enhance its stability and skin penetration. The final compound is purified and dried for use in cosmetics.

What does PALMITOYL TETRAPEPTIDE-7 do in a formulation?

HUMECTANT|
SKIN CONDITIONING

Safety Profile

Palmitoyl Tetrapeptide-7 is considered safe for topical use in cosmetics, with a low risk of irritation or sensitization. It is non-toxic and suitable for most skin types, including sensitive and aging skin. Clinical studies show minimal adverse reactions, though patch testing is advised for individuals with highly reactive skin. It is generally used in concentrations of 2% to 5% in formulations.

PALMITOYL TETRAPEPTIDE-7 alternatives

PALMITOYL TETRAPEPTIDE-7 technical profile

Property Values
pH 4.5- 6.0
Solubility Highly soluble in water
Viscosity Low

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