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NONAPEPTIDE-1

Last update on Nov 11, 2024
Nonapeptide-1 is a synthetic peptide used in cosmetics primarily for its skin-brightening and anti-aging properties. It is known for its ability to inhibit melanin production and promote an even skin tone. It is also believed to have an overall brightening effect on the skin, enhancing radiance and reducing the appearance of dullness. Nonapeptide-1 typically appears as a white to off-white powder when in its raw form. The powder is generally fine and uniform in texture, allowing for easy incorporation into various cosmetic products such as serums, creams, and lotions. As with any active ingredient, careful formulation and consideration of individual sensitivities are essential for optimal results.
CAS Number: 158563-45-2Chem/IUPAC Name: Nonapeptide-1EINECS/ELINCS No: COSING REF No: 57418

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What is NONAPEPTIDE-1 used for?

Nonapeptide-1 is quite useful in cosmetics for inhibiting melanin production by reducing the activity of the enzyme tyrosinase, effectively helping to lighten hyperpigmentation, dark spots, and uneven skin tone. It is potent for skin brightening and anti aging - making it a popular ingredient in products like serums and creams that target discoloration. Additionally, Nonapeptide-1 promotes collagen synthesis, which enhances skin elasticity and reduces the appearance of fine lines and wrinkles. It is suitable for various skin types, including sensitive skin, and is often incorporated into moisturizers, sunscreens, and anti-aging products for its overall skin-enhancing benefits.

Origin

Nonapeptide-1 is synthesized through solid-phase peptide synthesis (SPPS), a method that allows for the sequential addition of amino acids to form the peptide chain. This process involves coupling protected amino acids onto a resin, followed by deprotection and purification steps to yield the final product. The resulting peptide is then purified, typically using high-performance liquid chromatography (HPLC), to ensure its quality and potency.

What does NONAPEPTIDE-1 do in a formulation?

MOISTURISING|
SKIN CONDITIONING|
SMOOTHING

Safety Profile

Nonapeptide-1 is safe for topical use in cosmetic formulations, with a low risk of irritation or adverse reactions. Clinical studies have shown it to be well-tolerated by most skin types, including sensitive skin. However, patch testing is recommended prior to widespread use, especially for individuals with known sensitivities.

NONAPEPTIDE-1 alternatives

NONAPEPTIDE-1 technical profile

Property Values
pH 4.5-6.5
Solubility Soluble in water
Viscosity Low to moderate

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