Hexapeptide-9 is a synthetic peptide consisting of six amino acids. It is used in cosmetics for its ability to promote skin regeneration and reduce signs of aging. It is specifically designed to support the skin's natural repair processes and enhance the production of key proteins like collagen, which contribute to a firmer and more youthful complexion. Overall, it enhances skin texture and addresses issues like roughness and dryness. In its raw form, Hexapeptide-9 appears as a white to off-white powder that is easy to blend into various cosmetic formulations without altering the sensory properties. The chemical formula of Hexapeptide-9 is C24H38N8O9.
CAS Number: 1228371-11-6Chem/IUPAC Name: Hexapeptide-9EINECS/ELINCS No: COSING REF No: 56433Products with HEXAPEPTIDE-9
With samples available
SHINE+ Elastomeptide
by Uniproma Chemical
- Original documents
ActiTide® Bouncera
by Uniproma Chemical
- Original documents
What is HEXAPEPTIDE-9 used for?
Hexapeptide-9 is a multifunctional ingredient used in cosmetics for its skin-rejuvenating and anti-aging properties. It promotes collagen synthesis, helping to reduce the appearance of wrinkles, fine lines, and sagging skin, making it a key ingredient in anti-aging creams and serums. It enhances skin elasticity and firmness, improving overall texture and tone. Known for its reparative effects, Hexapeptide-9 accelerates wound healing and reduces the appearance of scars, including acne scars. It is commonly found in moisturizers, eye creams, and post-treatment products to support skin barrier recovery. Its ability to hydrate and smooth skin makes it ideal for mature, dry, or damaged skin.
Origin
Hexapeptide-9 is synthesized using solid-phase peptide synthesis (SPPS), a precise laboratory method. In this process, individual amino acids are sequentially bonded to form a six-amino-acid peptide chain. Protective groups ensure the correct sequence and prevent unwanted reactions. Once the chain is complete, it is cleaved from the solid support and purified, often through chromatography, to ensure high purity and stability. Sometimes, a fatty acid is added to enhance skin penetration.
What does HEXAPEPTIDE-9 do in a formulation?
SKIN CONDITIONING|
SMOOTHINGSafety Profile
Hexapeptide-9 is considered safe for use in cosmetics when included at appropriate concentrations. It is biocompatible, mimicking natural skin peptides, and generally well-tolerated by most skin types. Clinical studies and industry testing indicate low potential for irritation or allergic reactions, even with long-term use. However, as with any active ingredient, patch testing is recommended for individuals with sensitive or reactive skin.
HEXAPEPTIDE-9 alternatives
HEXAPEPTIDE-9 technical profile
| Property | Values |
| pH | 5-7 |
| Solubility | Soluble in water; insoluble in oil |
Formulations with HEXAPEPTIDE-9
No data available
By Application
No data available