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GLUCOSE

Last update on Jul 2, 2026

Glucose is a simple sugar (monosaccharide) and one of the most fundamental humectants in cosmetics. It effectively attracts and retains moisture while providing a smooth skin feel. Naturally occurring in the skin as part of the Natural Moisturizing Factor (NMF), it is widely used in moisturizers, serums, toners, masks, and oral care products for hydration, mild sweetness, and skin-conditioning benefits.

CAS Number: 50-99-7Chem/IUPAC Name: GlucoseEINECS/ELINCS No: 200-075-1COSING REF No: 34012

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What is GLUCOSE used for?

  • Humectant: Attracts and binds moisture to the skin. Frequently used in creams, serums, and lotions for effective hydration.
  • Skin conditioning: Helps maintain skin softness and smoothness. Common in hydrating and soothing formulations.
  • Flavoring / Sweetener: Provides mild sweetness in oral care products. Used in toothpastes and mouthwashes.

Origin

Glucose is primarily obtained through the hydrolysis of starch from corn, wheat, or potatoes. It can also be derived from other plant sources. For cosmetic use, it is highly purified and available as a white crystalline powder or aqueous solution (often 70% glucose syrup).

What does GLUCOSE do in a formulation?

HUMECTANT|
SKIN CONDITIONING|
FLAVOURING

Safety Profile

Glucose is considered extremely safe for cosmetic use with the lowest hazard rating from EWG (1). The CIR Expert Panel has assessed it as safe as used. It is non-irritating, non-sensitizing, and non-comedogenic, making it suitable for all skin types, including sensitive and baby skin. Approved by the EU COSING database for humectant, skin conditioning, and flavoring functions in rinse-off and leave-on products.

GLUCOSE alternatives

GLUCOSE technical profile

PropertyValues
Boiling PointDecomposes
Melting Point146°C
pH5.0 - 7.0 (10% aqueous)
SolubilityHighly soluble in water
ViscosityLow