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CI 45380

Last update on Jun 28, 2024

CI 45380 is a cosmetic colorant used in products like lipsticks, blushes, and eyeshadows. It gives a deep red color to formulations and serves a primary role in decorative cosmetics. In its raw form, this ingredient appears as a dark red-brown or rust colored powder. Additionally, it is also known by its other names such as Red 22 Lake and Red 21. CI 45380 has a synthetic origin and is commonly produced from coal tar or petroleum sources. Due to this, it has high use restrictions as the colorant may cause sensitivity or irritation on the skin.

CAS Number: 17372-87-1 / 548-26-5Chem/IUPAC Name: Disodium 2-(2,4,5,7-tetrabromo-6-oxido-3-oxoxanthen-9-yl)benzoateEINECS/ELINCS No: 241-409-6COSING REF No: 32769

Products with CI 45380

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With samples available

D&C RED 22

by DKSH

INCI: CI 45380

Sustainable option
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Original documents

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Disodium Eosine

by M-Kube

INCI: CI 45380

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SR43

by Artec Chemical

INCI: CI 45380

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What is CI 45380 used for?

CI 45380 is widely used in the cosmetics industry due to its vibrant red color. It is commonly found in a variety of products, including lipsticks, lip glosses, blushes, and eyeshadows, where it imparts a bright, appealing hue. The dye is also used in nail polishes, making them more visually striking. Additionally, CI 45380 is utilized in temporary hair color products. Its stability and consistency make it a preferred choice for formulating high-quality, long-lasting cosmetic products, ensuring they maintain their color and appeal throughout their shelf life.

Origin

CI 45380 is synthesized through a process involving the nitration of aromatic hydrocarbons, such as those found in petroleum or coal tar. The nitrated compounds undergo sulfonation to introduce sulfonic acid groups, followed by diazotization to form a diazonium salt. This diazonium compound is then coupled with a suitable coupling agent to produce the final azo dye. The product is purified, filtered, and dried, resulting in the bright red pigment.

What does CI 45380 do in a formulation?

COSMETIC COLORANT|

HAIR DYEING

Safety Profile

CI 45380 is generally considered safe for use in cosmetics when used within regulated concentrations. It has been approved by regulatory bodies such as the FDA for use in external cosmetic applications. However, some individuals may experience skin irritation or allergic reactions, particularly with sensitive skin. Performing a patch test prior to full application is recommended. Additionally, CI 45380 is halal and kosher certified.