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CHLORHEXIDINE DIGLUCONATE

Last update on Apr 7, 2023
Chlorhexidine digluconate, also known as clorexidina or chlorhexidine gluconate solution, is a commonly used ingredient in cosmetic and personal care products like skin cleansers. It appears in the form of white crystalline powder and has a slightly bitter taste, but it is mostly odorless. Chlorhexidine digluconate is well known for its antibacterial and antifungal properties. It is effective against a wide range of microorganisms, including those that cause skin infections.
CAS Number: 18472-51-0Chem/IUPAC Name: D-Gluconic acid, compound with N,N''-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediamidine (2:1)EINECS/ELINCS No: 242-354-0COSING REF No: 32659

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What is CHLORHEXIDINE DIGLUCONATE used for?

Chlorhexidine Digluconate is a miracle ingredient that is used in a wide range of personal care products as it is a great preservative.
  • Skin care: It is used in cleansers, toners, and acne treatments to help control bacteria and prevent infection. It is also used in wound care products to prevent infection and promote healing
  • Hair care: It is beneficial in preventing dandruff and scalp infections. It can commonly be found in shampoos and conditioners and is also used in a range of hair styling products to prevent the growth of bacteria and fungi on the scalp and hair

Origin

Chlorhexidine digluconate is synthesized from chlorhexidine base and gluconic acid through esterification. The resulting yellowish-brown, aqueous solution contains 20% chlorhexidine digluconate. The synthesis process is carefully controlled to ensure purity and quality of the final product.

What does CHLORHEXIDINE DIGLUCONATE do in a formulation?

ANTIMICROBIAL|
ORAL CARE|
PRESERVATIVE

Safety Profile

Chlorhexidine digluconate is generally considered safe for use in cosmetic and personal care products. However, it may not be suitable for everyone and therefore, it is always recommended to perform a patch test, especially on sensitive skin. Chlorhexidine digluconate is also unlikely to be comedogenic as it is not an oil-based ingredient, which is the primary cause of pore blockage. Being a synthetic compound, chlorhexidine digluconate can be considered vegan but it also depends on the source and production process of the ingredient.

CHLORHEXIDINE DIGLUCONATE technical profile

Property Values
Boiling Point 641.4°C
Melting Point 134-136°C
pH 5.0-7.0
Solubility Highly soluble in water
Viscosity Low