BeriCos® PAD

Potassium Azeloyl Diglycinate. BeriCos® PAD by Beri Pharma is a whitening-, brightening-, anti-acne-, anti-inflammatory-, anti-dandruff-, and repairing agent. It is an innovative multifunctional skincare active ingredient that significantly enhances water solubility and bioavailability through the molecular combination of azelaic acid with glycine in potassium salt form.

• Compared to conventional azelaic acid, its modified molecular structure offers superior mildness and stability while maintaining efficacy at low pH levels.
• It effectively helps avoid common irritation reactions, such as stinging and redness, typically associated with traditional azelaic acid.
• It exhibits a unique "triple synergistic mechanism": the glycine moiety enhances transdermal absorption, potassium ions maintain stratum corneum hydration, and the azelaic acid core provides sustained release of active components.
• It inhibits tyrosinase activity, thereby reducing melanin synthesis through competitive binding to the enzyme’s active sites.
• It also blocks melanosome transfer by downregulating PAR-2 signaling between keratinocytes and melanocytes.
• Additionally, its glycine structure provides antioxidant benefits by scavenging free radicals.
• It helps control sebum production by decreasing secretion through the inhibition of 5α-reductase.
• It enhances hydration by increasing natural moisturizing factor (NMF) production through filaggrin degradation.
• It strengthens the skin barrier by upregulating claudin-1 and occludin expression.
Additionally, it helps maintain the skin’s acid mantle.
• It is used in cream, lotion, essence and facial mask.
• BeriCos® PAD has a shelf life of 3 years.