Glucosylrutin is a water-soluble, stabilized derivative of rutin (a natural flavonoid glycoside from Sophora japonica or buckwheat) obtained through enzymatic glucosylation. The addition of a glucose unit significantly improves solubility, stability, and bioavailability compared to native rutin. It is one of the most potent flavonoid antioxidants used in modern cosmetics. It offers strong protection against oxidative stress, UV-induced damage, and inflammation. This pale yellow to beige powder or solution is widely used in anti-aging serums, day creams, sunscreens, brightening treatments, after-sun products, and sensitive skin formulations for photoprotection, redness reduction, and improved skin resilience.
Products with GLUCOSYLRUTIN
With samples available
AC-HPR-W2 SACOS PRO
by SOHO ANECO Chemicals
GRANACTIVE RETINOID™ PRO+
by Grant Industries
- Sustainable option
What is GLUCOSYLRUTIN used for?
- Antioxidant protection: Neutralizes free radicals and protects against ROS (reactive oxygen species) induced by UV, pollution, and blue light. Frequently used in day creams, serums, and sunscreens for prevention of photoaging and oxidative damage.
- Skin conditioning / Barrier support: Strengthens skin barrier and improves microcirculation. Ideal for anti-aging products, redness-reducing treatments, and formulations targeting sensitive or reactive skin.
- Anti-inflammatory & soothing: Reduces inflammation and calms irritation. Common in after-sun care, rosacea-friendly products, and post-procedure formulations for comfort and recovery.
- Brightening support: Helps inhibit tyrosinase and reduce hyperpigmentation. Used in brightening serums and spot correctors for more even skin tone.
Origin
Glucosylrutin is produced biotechnologically by enzymatic glycosylation of rutin (extracted from Sophora japonica buds or buckwheat) using a glucosyltransferase enzyme. This process attaches a glucose molecule to the rutin structure, greatly enhancing water solubility (from ~0.01 % for rutin to >20% for glucosylrutin) and photostability. It is 100% natural-origin, vegan, and widely available in high-purity grades for clean and premium formulations.
What does GLUCOSYLRUTIN do in a formulation?
ANTIOXIDANT|
SKIN PROTECTING|
SKIN CONDITIONING|
SOOTHINGSafety Profile
Glucosylrutin is considered safe for cosmetic use. It has a very low hazard rating from EWG (typically 1) and minimal concerns for irritation, sensitization, or toxicity at typical concentrations (0.1-3%; often effective at 0.5-1%). It is non-comedogenic, well-tolerated across skin types (including sensitive and reactive), and shows no significant systemic absorption. Rare allergic reactions may occur in individuals sensitive to rutin or flavonoids. Patch testing is recommended.
GLUCOSYLRUTIN alternatives
GLUCOSYLRUTIN technical profile
| Property | Values |
| Boiling Point | Decomposes (>250°C) |
| Melting Point | ~180-200°C |
| pH | 4.0 - 7.0 |
| Solubility | Highly water-soluble (>20 g/100 mL) |
Formulations with GLUCOSYLRUTIN
No data available
By Application
No data available