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DISODIUM EDTA

Last update on Mar 3, 2026

Disodium EDTA (chemical formula - C10H16N2Na2O8) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in a product. This white, water-soluble solid is widely used to bind to metal ions like iron and calcium ions and prevent the deterioration of cosmetics and personal care products. Disodium EDTA thus enhances stability of cosmetics.

CAS Number: 139-33-3Chem/IUPAC Name: Disodium dihydrogen ethylenediaminetetraacetateEINECS/ELINCS No: 205-358-3COSING REF No: 33604

Products with DISODIUM EDTA

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Unipertan™ VEG-2002

by Givaudan

INCI: ACETYL TYROSINE | ADENOSINE TRIPHOSPHATE | BUTYLENE GLYCOL | DISODIUM EDTA | HYDROLYZED VEGETABLE PROTEIN | PVP | SODIUM RIBOFLAVIN PHOSPHATE | AQUA
  • Sustainable option

Microsponge® C116A

by Minerals Technologies

INCI: RETINOL | METHYL METHACRYLATE/GLYCOL DIMETHACRYLATE CROSSPOLYMER | TOCOPHERYL ACETATE | ASCORBIC ACID | DISODIUM EDTA | PROPYL GALLATE | POLYSORBATE 20 | BHT

What is DISODIUM EDTA used for?

Disodium EDTA is widely used and can be found in moisturizers, skincare and cleansing products, personal cleanliness products, bath soaps, shampoos and conditioners, hair dyes, hair bleaches, and many other product types. Disodium EDTA and the related ingredients bind to metal ions which inactivates them. The binding of metal ions helps prevent the deterioration of cosmetics and personal care products thus enhancing their stability. It also helps to maintain clarity, protect fragrance compounds, and prevent rancidity. It is used up to 0.85% concentration in leave-on products. For both skin care and hair care applications, it prevents metal ions from depositing on the surface.

Origin

Disodium EDTA is mainly synthesized from ethylenediamine (1,2-diaminoethane), formaldehyde, and sodium cyanide. This route yields the tetrasodium EDTA, which is converted in a subsequent step into the acid forms.

What does DISODIUM EDTA do in a formulation?

CHELATING

Safety Profile

Disodium EDTA is not classified to be potentially toxic or harmful. It is designated as safe for general or specific use. It has a low hazard rating from EWG (typically 2) with minimal concerns for irritation or sensitization. It shows very low skin penetration and no significant systemic toxicity at cosmetic levels.

DISODIUM EDTA technical profile

PropertyValues
Melting Point242°C
pH5.3
SolubilitySoluble in water