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CI 45370

Last update on Oct 24, 2025

CI 45370, also known as Orange 5, is an orange dye used in cosmetics to give products an orange or reddish color. This enhances product appearance and makes them more appealing to the users. CI 45370 works well in oil-based cosmetics and offers a vibrant pigmentation and good color stability. It can be found in lipsticks, lip glosses, blushes, bronzers, nail polishes, eyeshadows, and mascaras. However, Orange 5 has high use restrictions and is banned in several countries due to its potential risks of irritation. It is not approved by the FDA for use around the eyes and can only be used in limited amounts in other beauty products.

CAS Number: 4372-02-5 / 596-03-2Chem/IUPAC Name: 4',5'-Dibromo-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one and its permitted lakes and saltsEINECS/ELINCS No: 224-468-2 / 209-876-0COSING REF No: 32768

Products with CI 45370

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With samples available

Eospoly® UVB Orange 5

by The Innovation Company

INCI: ALUMINA | CI 45370 | CI 77891 | LIMNANTHES ALBA SEED OIL | SILICA
  • Sustainable option

What is CI 45370 used for?

  • Colorant - CI 45370 imparts a vibrant orange or reddish orange color to makeup and personal care formulations. It enhances the visual appeal of products and provides a warm tint to products like lipsticks and lip balms.

Origin

CI 45370 is a synthetic dye made from coal tar or petroleum sources. In its raw form, it appears as an odorless, bright orange-red powder. For use in cosmetics, it is thoroughly purified to remove carcinogenic contaminants. The chemical formula of CI 45370 is C20H10Br2O5.

What does CI 45370 do in a formulation?

COSMETIC COLORANT

Safety Profile

CI 45370 can be safely used in cosmetics only if it meets the FDA and EU purity standards. This is why it is important to source this ingredient from certified suppliers. In any case, it is not approved for use in cosmetics meant to be used on or around the eyes. Patch testing must be done prior to full application of products containing CI 45370. Additionally, this synthetic colorant is suspected to be an environmental toxin and is harmful to aquatic life.

CI 45370 technical profile

PropertyValues

Boiling Point

633.7°C ± 55.0°C

Melting Point

270°C - 273°C

pH

6 - 8

Solubility

Soluble in water and oil

Formulations with CI 45370

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By Application

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