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CALCIUM THIOGLYCOLATE: INCI Ingredient

Last update on Jul 2, 2026

Calcium Thioglycolate is the calcium salt of thioglycolic acid. It is primarily used as a chemical depilatory agent that breaks disulfide bonds in hair keratin, allowing for easy removal of unwanted hair. This ingredient is commonly found in cream, lotion, and gel depilatory products for the face, body, and sensitive areas. It provides effective hair removal while being relatively gentle compared to mechanical methods when properly formulated.

CAS Number: 814-71-1Chem/IUPAC Name: Calcium bis(mercaptoacetate)EINECS/ELINCS No: 212-402-5COSING REF No: 32352

Products with CALCIUM THIOGLYCOLATE

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JADEPIL CTG

by Hangzhou Jarsin Chemical Technology

INCI: CALCIUM THIOGLYCOLATE

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Calcium Thioglycolate

by Huwell Chemicals

INCI: CALCIUM THIOGLYCOLATE

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Calcium Thioglycolate trihydrate

by Susonity

INCI: CALCIUM THIOGLYCOLATE

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What is CALCIUM THIOGLYCOLATE used for?

Depilatory agent: Breaks down hair structure for chemical hair removal. Frequently used in depilatory creams, lotions, and gels for face and body.
Reducing agent: Reduces disulfide bonds in keratin. Ideal for professional and at-home hair removal products.
pH adjuster / stabilizer: Helps maintain optimal alkaline pH required for depilatory action in formulations.

Origin

Calcium Thioglycolate is produced synthetically by the reaction of thioglycolic acid with calcium hydroxide or calcium carbonate. The resulting salt is purified and often supplied as a trihydrate for better stability. It is a manufactured inorganic-organic compound specifically developed for cosmetic depilatory applications.

What does CALCIUM THIOGLYCOLATE do in a formulation?

DEPILATORY|

KERATOLYTIC|

REDUCING

Safety Profile

Calcium Thioglycolate is considered safe for cosmetic use when formulated at regulated concentrations (typically up to 5-6% as thioglycolic acid equivalent) with proper pH control. It has a moderate hazard rating from EWG due to its potential for skin irritation and sensitization if not properly buffered. It must be used with caution on sensitive skin and requires thorough rinsing after application. The EU limits its concentration and requires specific warnings on labeling.