Benzophenone-1 is a synthetic compound used primarily in cosmetics and personal care products as a UV filter and stabilizer. It is part of a larger class of chemicals known as benzophenones, which are characterized by their ability to absorb UV radiation, helping to protect skin and products from the damaging effects of sun exposure. Benzophenone-1 is responsible for stabilizing formulations by preventing degradation of other ingredients, in turn, maintaining the product’s efficacy and extending their shelf life. In its raw form, it typically appears as a white to pale yellow crystalline powder with a sweet odor. The chemical formula of Benzophenone-1 is C13H10O.
As of 27 March, 2025, the SCCS concludes that Benzophenone-1 is not safe for use in cosmetic products due to genotoxicity concerns, clear estrogenic activity, weak anti-androgenic effects and possible thyroid disruption.
Products with BENZOPHENONE-1
Mfsorb 501
by MFCI
Aegivita UV-BP1
by Aegis
Sunsafe® BP1
by Uniproma Chemical
What is BENZOPHENONE-1 used for?
Benzophenone-1 is an effective UV filter and stabilizer. Its primary function is to absorb harmful ultraviolet radiation, protecting the skin from sunburn and photoaging. It is commonly found in sunscreens, moisturizers, and makeup products such as foundations and powders, enhancing their stability against UV-induced degradation. Additionally, Benzophenone-1 helps maintain the integrity of fragrances and colorants, preventing them from breaking down in sunlight. Its lightweight nature makes it suitable for a variety of formulations, ensuring effective sun protection while contributing to the overall performance of cosmetic products.
Origin
Benzophenone-1 is synthesized through a Friedel-Crafts acylation reaction, where benzoyl chloride reacts with phenol in the presence of a Lewis acid catalyst, typically aluminum chloride. This reaction forms a benzophenone structure by introducing a carbonyl group to the phenolic ring. The resulting product is then purified through recrystallization or distillation to obtain high-purity Benzophenone-1.
What does BENZOPHENONE-1 do in a formulation?
Safety Profile
Benzophenone-1 is generally considered non-toxic for cosmetic use when applied at recommended concentrations - ranging from 0.5% to 10%. However, patch tests must be performed before use. Additionally, there are concerns about the environmental impact of benzophenones, particularly regarding their effects on marine ecosystems. Therefore, this ingredient faces some regulations and restrictions in certain regions.
BENZOPHENONE-1 alternatives
BENZOPHENONE-1 technical profile
| Property | Values |
| Boiling Point | 305.4°C |
| Melting Point | 48.5°C |
| Solubility | Sparingly soluble in water; soluble in organic solvents |
| Viscosity | Low |
